Alpha-Thalassemia is an inherited blood disorder that impairs the body’s ability to produce hemoglobin, the protein in red blood cells that carries oxygen.

There are multiple forms of Alpha-Thalassemia ranging from mild to very severe or fatal, depending on the location and nature of the gene mutations.

The form of Alpha Thalassemia known as Hemoglobin H disease causes moderate to severe anemia. Symptoms may also include susceptibility to infection, enlarged spleen, and bone deformities.

Children born with the most severe form, Alpha-Thalassemia major, usually die before birth or in infancy.

Treatment may include blood transfusions and medication to prevent toxic buildup of iron in the body.

Alpha-Thalassemia is more commonly found in people from Southeast Asia and
Southern China, Africa, the Middle East, and India.

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